Quinton de Kock and Joe Root hit half-centuries.
Beginning the day on 88/6, Quinton de Kock (76) and Dwaine Pretorius (37) stretched the total to 183 runs when the 10th wicket fell. Mark Wood impressed with figures of 5/46, while Chris Woakes and Ben Stokes picked two wickets apiece.
South Africa was asked to chase down 466 runs with two days to go, as England led by 465 runs. This is going to be a tough ask for the Proteas side, given their recent form and it will need a herculean effort from Dean Elgar, Faf du Plessis, Quinton de Kock, and co. to win from here and stop England from winning the match and the series.
BRIEF SCORES:
ENG 400 & 248 (J ROOT 58, D SIBLEY 44; B HENDRICKS 5/64) AND SA 183 (Q DE Kock 76, D PRETORIUS 37; M WOOD 5/46)
Stumps, Day 3: England lead by 465 runs with 0 wickets remaining