Pakistan will face England in a three-Test, three-T20I series in August-September.
The Irishmen will arrive in England on July 18 and will set their base at the Ageas Bowl, Southampton before facing the last year's World Cup champions in three ODIs at the same venue, with the second and third matches of the series taking place respectively on August 1 and 4.
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England has taken on Ireland in 10 ODIs in the history of the two countries so far, losing only once, famously at the 2011 World Cup in Bangalore.
The Pakistan team has already arrived in the UK on June 28 and is currently going through its 14-day quarantine period after testing COVID-19 negative amid the pandemic.
They are currently training in Worcestershire and will then shift base to Derbyshire to play inter-squad warm-up matches ahead of the first Test of the three-match series, now confirmed to kickstart on August 5 at Old Trafford ground in Manchester.
Southampton will host the next two Test matches from August 13th to 17th and 21st to 25th, respectively.
Teams will then move back to the Old Trafford for the three T20Is, with the first one on August 28th, followed by games on the 30th and 1st of September.
All matches will be played in a bio-secure bubble while adhering to the highest safety protocols in wake of the viral outbreak that has led to a global health crisis.
International cricket returns on July 8 via the England-West Indies Test series in Southampton.
"Confirmation of these matches against Ireland and Pakistan is another important step for our game as we begin to safely stage international cricket again, but also to minimise the impact the Covid-19 pandemic has had, and will continue to have, on cricket at all levels," ECB Chief Executive, Tom Harrison, said in a statement.
“It has taken significant effort and expertise to allow us to reach a position where cricket is now ready and able to return to the field of play from the elite level to recreational cricket."
"We owe a significant debt of gratitude to the players, staff and administrators of the Cricket West Indies, Cricket Ireland, and the Pakistan Cricket Board for their willingness and co-operation to get international cricket back up and running and allow these matches to be staged," he added.
Full England v Ireland fixture list:
1st ODI: Thursday 30 July, The Ageas Bowl (2.00 pm BST)
2nd ODI: v Saturday 1 August, The Ageas Bowl (2.00 pm BST)
3rd ODI: v Tuesday 4 August, The Ageas Bowl (2.00 pm BST)
Full England v Pakistan fixture list:
1st Test: 5-9 August, Emirates Old Trafford (11.00 am BST)
2nd Test: 13-17 August, The Ageas Bowl (11.00 am BST)
3rd Test: 21-25 August, The Ageas Bowl (11.00 am BST)
1st T20I v Pakistan: Friday 28 August, Emirates Old Trafford (6.00 pm BST)
2nd T20I v Pakistan: Sunday 30 August, Emirates Old Trafford (2.30 pm BST)
3rd T20I v Pakistan: Tuesday 1 September, Emirates Old Trafford (6.00 pm BST).